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Established as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on laboratory topics, including KPIs for the IVF laboratory, Quality control in the cloud, Artificial Intelligence, AI in gamete and embryo selection, Demystifying vitrification, Microfluidics, Gene editing, Disaster management, and Early human embryo development revealed by static imaging. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.

Table of Contents

1. Updated guidelines for setting up an assisted reproduction technology laboratory
2. Quality control maintaining stability in the
3. KPIs for the IVF laboratory
4. QC in the Clouds-Digitizing quality control
5. The assisted reproduction technology laboratory: Current standards.
6. Evaluation of sperm
7. Sperm preparation techniques and advanced sperm selection for intracytoplasmic sperm injection
8. Sperm chromatin assessment
9. Oocyte retrieval and selection
10. Preparation and evaluation of oocytes for intracytoplasmic sperm injection - Irit Granot and Nava Dekel.
11. Use of IVM in a clinical setting: What is its role in ART?
12. Intracytoplasmic sperm injection: Technical aspects
13. Human embryo biopsy procedures
14. Analysis of fertilization - Thomas Ebner.
15. Culture Systems for the Human Embryo.
16. Embryo selection through the analysis of morphology and physiology
17. Evaluation of embryo quality: Time-lapse imaging to assess embryo morphokinesis
18. Artificial Intelligence (AI)
19. AI in Gamete and Embryo Selection
20. Demystifying vitrification.
21. Vitrification of the Human Oocyte.
22. The human embryo: vitrification
23. Managing an oocyte bank
24. Severe male factor infertility: Genetic consequences and recommendations for genetic testing
25. Preimplantation genetic testing for aneuploidy to improve clinical outcomes
26. Diagnosis of endometrial receptivity, embryo–endometrial dialog, and endometrial microbiome
27. Artificial Gametes: Oocytes
28. How microfluidics and microfabrication will improve diagnosis and treatment in Human ART
29. Genome Editing in Human Reproduction
30. Designing Disaster Plans for IVF Laboratories
31. Early human embryo development revealed by s