First, the hoof thoroughly, removing debris and necrotic material prior to application. Apply Kopertox daily to the affected hooves until fully healed. Recommended as an aid in treating horses and ponies with thrush due to organisms susceptible of copper naphthenate. For over 45 years, Intrepid International has been the leading global manufacturer and distributor of products for horse and rider. We strive to provide quality products at reasonable prices with superior customer service. Package contains (1) Kopertox for Horses and Ponies - Water-Resistant Protection without Bandaging, 16oz. For external use only. For animal use only. Keep out of reach of children. Not for use on horses intended for food.