Meet Frost, Morgan, and Nell—a wealthy, gorgeous group of New York City moms, the queen bees of downtown Manhattan. Their children attend Atherton Seminary, the top private school in the city, and their social lives revolve around elaborate themed parties.

On the first day of school, the arrival of a new mom and mysterious beauty from Miami named Sofia shakes up their world. When Sofia quickly integrates herself into their clique, inexplicably bad things start to happen to the women. Frost is the victim of a hit-and-run electric scooter incident. Nell's dream of launching a fashion line is thwarted when the clothing samples cause people to break out in a rash. Morgan's new sound bath spa is robbed at gunpoint by a moped-driving thief. Morgan declares it all a "negative event cluster," but the other women aren't so sure.

Is someone at school out to get them? Another mom with a vendetta? Let’s not forget to mention the handsome headmaster, Dr. Broker, who every mom has a crush on (and one of them might be sleeping with).

Spanning the course of one eventful fall in New York, ending with a Surrealist New Year's Eve ball—and a possible death, Mean Moms is part satire of upper crust mom-ing and part mystery, interrogating the line between friendship and jealousy, and getting at the question of: What would happen if the woman standing next to you at school pick up was actually a sociopath?