The 64th Bombardment Squadron is an inactive United States Air Force unit that was last assigned to the 43rd Bombardment Wing at Little Rock Air Force Base, Arkansas, where it was inactivated on 31 January 1970.

The squadron was first activated in January 1941, as one of the original squadrons of the 43rd Bombardment Group. Following the attack on Pearl Harbor, the squadron participated in antisubmarine patrols until January 1942, when it moved to Australia and the Southwest Pacific Theater. It moved forward with US forces through New Guinea and the Philippines, moving to Ie Shima shortly before V-J Day for operations against Japan. It earned two Distinguished Unit Citations and a Philippine Presidential Unit Citation for combat operations. The squadron was inactivated in the Philippines in April 1946.